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Director: Peter Greste

Stars : Sarah Ferguson

Genre : Documentary | Short

IMDB Rating: 5.0

Release: 11 April 2017 (Usa)

Facebook: Cracking the Code :- Watch Facebook: Cracking the Code on, Stephen Damiani’s persona burns through this story as an intelligent, highly focused fanatic. How else do you save your boy who has been diagnosed with a rare brain disorder, so rare it has no name? All you are told is that the myelin – the insulation that surrounds the nerves of the brain – is missing or breaking down. For little Massimo this meant the signals from the brain weren’t travelling down the nerve pathways. Six years ago, when he was 12 months old, Massimo’s developmental milestones stopped and he was regressing. He could not stand or speak. Stephen and his wife Sally were losing their son; and his prognosis was dire.The neurologists’ initially diagnosed a form of Leukodystrophy​ – a blanket term covering a group of rare inherited or genetic disorders. But in 2009 it was impossible to find the exact genetic cause. Stephen has a background in construction economics and risk management, he is not a scientist but he hit the internet like a man possessed and taught himself genomics.He joined forces with neurologists across the globe, including Queensland scientist Ryan Taft, in order to analyse the genomes or DNA blueprints of not only Massimo but himself and his wife. In effect, they used genome sequencing in order to find a single genetic variation.They finally hit the jackpot: Massimo has a previously unclassified condition now known as HBSL caused by a mutation in the DARS gene. Stephen and Sally now hope to halt the progress of Massimo’s condition. Furthermore, Taft and Damiani have developed a tool with the potential to diagnose and treat diseases as widespread as diabetes and cardiovascular disease.The writing of Cracking the Code is attributed to the Damianis “with” Dr Leah Kaminsky, but she is the one who pulled this complicated tale together. As the family’s GP, she was the conduit to specialists and treatments and an unfailing source of support.Kaminsky seamlessly inserts Stephen and Sally’s voices, allowing them to express the impact of their ordeal in their own words. She also emphasises that it was the Damianis’ strength and determination that heralded this international breakthrough in medical science.A glossary would help the layperson, but overall, Cracking the Code is taut and fascinating.

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